Biostimulators add volume and improve skin’s quality by stimulating the body’s natural ability to build collagen. For facial rejuvenation, the treatment involves injecting Sculptra into areas of flattening or hollowing due to age and weight-loss associated volume loss. This procedure differs from injection of hyaluronic acid (HA) fillers that are more useful for highlighting or creating fullness over prominences or near the lower eyes or lips. Sculptra can be used in the face, neck, hands, and buttocks.